WALL·E·NATOR: After getting Wolverine's jacket instead of his insurance, WALL·E·NATOR starts a rampage against producers of garbage.
Extreme Renovation: House Edition: Ty Pennington takes over Superman's Fortress of Solitude.
- Opening Scene
- WALL·E·NATOR (Spoof on WALL·E / Movie Parody of the Terminator)
- Animated Marginals segment
- Which of These Things is Not Like the Other? (Cartoon) (Spoof on Miley Cyrus and Selena Gomez)
- Happy Charms (Cereal Parody of General Mills' Lucky Charms) (Ad Parodies segment)
- Nix Kidz Pix Lady turns into a nightmare monster (TV Parody of Nickelodeon's Kids Choice Awards) (Animated by Mike Wartella)
- MAD's Guide to Phobias (MAD's Guide to... segment) (Parody of Facebook and Voltron)
- The Morning Feeding (Cartoon) (Based on a comic by Tomas Bunk in MAD issue #383) (Source: http://www.madcoversite.com/mad383.html)
- The Spatula (TV Parody of the Bachelor) (Live-action Cartoon / Ad Parodies segment)
- The killer is in this room... (Animated by Mike Wartella)
- Spy vs. Spy - Splitting Torpedo (Spy vs. Spy segment)
- Where's Lady Gaga? (Where's Lady Gaga? segment) (Book Parody of Where's Waldo? / Spoof on Lady Gaga)
- You got "Toad" (Cartoon)
- Animated Marginals segment
- Build-a-Bieber (Store Parody of Build-a-Bear Workshop / Spoof on Justin Bieber) (Ad Parodies segment)
- Yell ''APE!'' to Request Stop (Cartoon)
- Extreme Renovation: House Edition (TV Parody of ABC's Extreme Makeover: Home Edition)
- 5-second cartoon: (from MAD's Guide to Phobias) Transform-a-phobia (TV Parody of Transformers) (5-second Cartoon segment)
- Main article: WALL·E·NATOR / Extreme Renovation: House Edition/Gallery
- Main article: WALL·E·NATOR / Extreme House Renovation (Transcript)
- This is the first time a Mike Wartella segment appeared before Spy vs. Spy, the first episode of MAD to have two Mike Wartella segments, the first time an Ad Parody was a Live-action Cartoon, and the first time Oscar the Grouch from Sesame Street showed up.
- And also, this is the first and SpongeBob SquarePants appeared, and Dr. Gregory House made an appearance in Extreme Renovation: House Edition.
- This is the second appearance of the Where's Lady Gaga? segment and the MAD's Guide to... segment, and the second time Justin Bieber appeared.
- This is the third episode of MAD where the second Animated Marginal is not directly after Spy vs. Spy. The first was Episode 2 and the second was Episode 3.
- Nix Kidz Pix is a parody of the Nickelodeon Kids' Choice Awards where people get green slime dumped on them.
- In Extreme Renovation: House Edition, Scrat from Ice Age makes a cameo, and Danny Phantom and Casper the Friendly Ghost were seen in the Phantom Zone the renovation crew opened accidentally.
- The sign in "Yell APE!" said "Push yellow tape to request stop."
- In WALL·E·NATOR, Alfred E. Neuman, Black Spy, and White Spy were in the office, and if you closely, you will see Optimus Prime and Sam Witwicky at the wedding.
- On the background on Build-a-Bieber, you get to see a Justin Bieber doll with big eyes and getting scared when a girl was holding him.
- On the background on the sketch "the Morning Feeding" there was bird wearing a red cap on a bench. This may be a parody of Mario.
- Jason Antoon - Lex Luthor, the Spatula Announcer, and MAD's Guide to Phobias Announcer
- Hugh Davidson - Wolverine and General Zod
- Larry Dorf - Shelby Forthright, Build-a-Bieber Guy, and Prime Minister
- Aldis Hodge - Usher, Sinestro, and Frog
- Jason Marsden - Ty Pennington, Commercial Boy, and Flint Lockwood
- Julia McIlvaine - Sam Sparks, Nix Kidz Pix Hostess, Build-a-Bieber Girl, and Mom
- Rachel Ramras - Little Girl, Commercial Girl, Build-a-Bieber Girl, and Mom
- Kevin Shinick - Himself, Which of These Things is Not Like the Other? Announcer, WALL·E, Superman, Oscar the Grouch, Happy, Bertram, Jor-El, SpongeBob SquarePants, Gregory House, and Justin Bieber Dolls